A p53-dependent response limits epidermal stem cell functionality and organismal size in mice with short telomeres.
Telomere maintenance is essential to ensure flexcon reverse osmosis water storage tank proper size and function of organs with a high turnover.In particular, a dwarf phenotype as well as phenotypes associated to premature loss of tissue regeneration, including the skin (hair loss, hair graying, decreased wound healing), are found in mice deficient